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  • QD-loaded poly(alkyl cyanoacrylate) nanoparticlesSoft Matter 2011, 7, 6187
  • Nanoparticles against cancer and AlzheimerACS Nano 2012, 6, 5866
  • Amyloid-beta peptide-binding nanoparticlesACS Nano 2012, 6, 5897
  • Nanoparticles for brain endothelial cell imagingChem. Commun. 2010, 46, 2602
  • Multifunctional squalene-based nanoparticlesChem. Commun 2014, 50, 5336
  • Lipid-containing polymer prodrug nanoparticlesChem. Mater. 2014, 26, 3606
  • Anticancer multifunctional polyester nanoparticlesChem. Mater. 2014, 26, 1834
  • Anticancer polyterpene prodrug nanoparticlesAngew. Chem., Int. Ed. 2013, 52, 6
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Welcome to my homepage

I'm a CNRS researcher in the group of Pr. Patrick Couvreur at Institut Galien Paris-Sud (UMR CNRS 8612), in the Faculty of Pharmacy of Châtenay-Malabry, University Paris-Sud 11, France.

The Institut Galien Paris-Sud aims to design, synthesize, characterize and evaluate new drug delivery systems for the controlled release and the targeting of drugs. Pr. Patrick Couvreur's research group is working on the use of nanomedicines for cancer therapy as well as neurodegenerative and infectious diseases.

My contributions in this multidisciplinary research group are based on advanced macromolecular synthesis, physico-chemistry of colloids and bioconjugation, in order to develop efficient and innovative polymer biomaterials and nanomedicines.

News


Award

[Nov 17, 2016]

Julien received the French Polymer Society (GFP) / French Chemical Society (SCF) award during the 45th GFP meeting in Marseille, France.

Presentation

[Nov 17, 2016]

Julien delivered an invited lecture titled "Drug-Initiated Synthesis of Polymer Prodrug Nanoparticles" at the 45th GFP meeting in Marseille, France.

Publication

[Nov 11, 2016]

Our collaborative article titled "Pulmonary Surfactant Protein A: A Mediated Enrichment of Surface-Decorated Polymeric Nanoparticles in Alveolar Macrophages" is accepted in Mol. Pharm. Congratulations to all!

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Publication

[Oct 7, 2016]

Our collaborative review article titled "Radical Ring-Opening Polymerization: Scope, Limitations and Application to (Bio)Degradable Materials" is accepted in Chem. Rev. Congratulations to all!

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Appointment

[Oct 5, 2016]

Julien has joined the editorial team of Chemistry of Materials (ACS) as Associate Editor.

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Presentation

[Sep 26, 2016]

Elise delivered a lecture titled "The Drug-Initiated Strategy: A Convenient Way to Design Polymer Nanoparticles for Anticancer Therapy" at the 4th Congress on Innovation in Drug Delivery: Site-Specific Drug Delivery, Antibes-Juan-les-Pins, France. Congratulations!

Presentation

[Aug 25, 2016]

Julien delivered an invited lecture titled "Comb-like PEG-based Vinyl Copolymers for Biomedical Applications" at the 252nd American Chemical Society National Meeting & Exposition, Philadelphia, USA.

Publication

[Aug 15, 2016]

Yinyin's article titled "Simple Synthesis of Cladribine-Based Anticancer Polymer Prodrug Nanoparticles with Tuneable Drug Delivery Properties" is accepted in Chem. Mater. Congratulations!

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Presentation

[Jul 12, 2016]

Julien delivered an invited lecture titled "Vinyl Polymers for Biomedical Applications" at the Warwick Polymer Conference 2016, University of Warwick, Coventry, UK.

Presentation

[Jul 8, 2016]

Julien delivered an invited lecture titled "Polymer Nanoparticles for Biomedical Applications" at the 7ème journée GFP-IdF, ICPME, Université Paris-Est, Thiais.

Publication

[Jun 3, 2016]

Johanna's article titled "Efficient Synthesis of 2-Methylene-4-Phenyl-1,3-Dioxolane, a Cyclic Ketene Acetal for Controlling the NMP of Methyl Methacrylate and Conferring Tunable Degradability" is accepted in Polym. Chem. Bravo!

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Presentation

[May 24, 2016]

Julien delivered an invited lecture titled "Degradable PEG-Based Materials by Nitroxide-Mediated Radical Ring-Opening Copolymerization" at the Belgian Polymer Group annual meeting 2016, Hasselt, Belgium.

Presentation

[Apr 7, 2016]

Julien delivered an invited lecture titled "Drug-Initiated Synthesis of Polymer Prodrug Nanoparticles" at the 10th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical (PBP) Technology, Glasgow, UK.

Cover

[Mar 22, 2016]

Julien's invited Perspective article entitled "Drug-Initiated Synthesis of Polymer Prodrugs: Combining Simplicity and Efficacy in Drug Delivery" made the front cover of Chemistry of Materials!

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Presentation

[Mar 14, 2016]

Yinyin delivered a lecture titled "Efficient Anticancer Polymer Prodrug Nanoparticles from Drug-Initiated Controlled/Living Radical Polymerization" at the 251st American Chemical Society National Meeting & Exposition, San Diego, USA. Congratulations!

Presentation

[Mar 7, 2016]

Julien delivered an invited lecture titled "Drug-Initiated Synthesis of Polymer Prodrug Nanoparticles" at the 11th International Conference and Workshop on Biological Barriers, Saarbrücken, Germany.

Publication

[Jan 29, 2016]

Julien's invited Perspective article titled "Drug-Initiated Synthesis of Polymer Prodrugs: Combining Simplicity and Efficacy in Drug Delivery" is accepted in Chem. Mater.

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Seminar

[Jan 27, 2015]

Julien presented two seminars titled "Advanced polymer nanoparticles against cancer and the Alzheimer's disease" and "Vinyl polymers for biomedical applications" at the Institute of Toxicology and Genetics (ITG) and at the Macromolecular Architectures (MacroArc) Research Team at the Karlsruhe Institute of Technology (KIT), respectively.

Publication

[Jan 10, 2016]

Our collaborative paper titled "Nitroxide-Mediated Polymerization of Vinyl Chloride at Low Temperature: Kinetic and Computational Studies" is accepted in Macromolecules.

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Publication

[Dec 25, 2015]

Our collaborative paper titled "Cyclopentyl Methyl Ether as a Green Solvent for Reversible-Addition Fragmentation Chain Transfer and Nitroxide-Mediated Polymerizations" is accepted in RSC Advances.

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Presentation

[Dec 20, 2015]

Julien delivered three lectures (incl. one as invited speaker) titled "Nitroxide-Mediated Radical Ring-Opening Copolymerization: A Single Cyclic Ketene Acetal Comonomer to Control the Polymerization of Methacrylates and to Confer Degradability", "Conjugation and Bioconjugation from α-Functional Polymers Obtained by Nitroxide-Mediated Polymerization (NMP) Initiated by N-Hydroxysuccinimidyl- or Azlactone-Functionalized Alkoxyamines" and "The Drug-Initiated Method: a Convenient Approach for the Synthesis of Efficient Polymer Prodrug Nanoparticles" at the International Chemical Congress of the Pacific Basin Societies (Pacifichem 2015), Honoluu, Hawai, USA.

Member

[Dec 03, 2015]

Welcome to Alexandre Bordat, the newest member of the group, who joined us as PhD.

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Presentation

[Nov 05, 2015]

Julien delivered an invited plenary lecture titled "Advanced Polymer Nanoparticles For Efficient Drug Delivery" at the Applied Nanotechnology and Nanoscience International Conference (ANNIC 2015), Paris, France.

Member

[Nov 03, 2015]

Welcome to Johanna Tran, the newest member of the group, who joined us as PhD.

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Press

[Oct 9, 2015]

Following his review article in Nature Chemistry, Julien was interviewed by the CNRS Institute of Chemistry on potential biomedical applications from degradable vinyl polymers.

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Cover

[Oct 1, 2015]

Vianney's Review article entitled "Degradable Vinyl Polymers for Biomedical Applications" made the front cover of Nature Chemistry!

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Member

[Oct 01, 2015]

Welcome to Daniele Vinciguerra, the newest member of the group, who joined us as PhD.

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Publication

[Sep 22, 2015]

Vianney's Review article titled "Degradable Vinyl Polymers for Biomedical Applications" is accepted in Nature Chemistry. Congratulations!

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Presentation

[Sep 02, 2015]

Julien delivered an invited oral presentation titled "The Drug-Initiated Method: A Convenient Way for the Synthesis of Efficient Anticancer Polymer Prodrug Nanoparticles" at the International Symposium on Amphiphilic Polymers, Networks, Gels and Membranes (APNGM15), Budapest, Hungary.

Member

[Sep 01, 2015]

Welcome to Nada Ibrahim, the newest member of the group, who joined us as Post-Doc.

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Presentation

[Jul 8, 2015]

Julien delivered an oral presentation titled "The Drug-Initiated Method: A New Route to More Potent Nanoparticles for Anticancer Therapy" in the "Highlights in Chemistry" symposium at the 2015 French Chemical Society meeting SCF'15, Lille, France.

Publication

[Jul 6, 2015]

Vianney's article titled "A Ring to Rule Them All: A Cyclic Ketene Acetal Comonomer Controls the Nitroxide-Mediated Polymerization of Methacrylates and Confers Tunable Degradability" is accepted in Chemical Communications. Congratulations!

This article is open access

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Cover

[Jul 2, 2015]

Elise's Review article entitled "Nitroxide-Mediated Polymerization of Methacrylic Esters: Insights and Solutions to a Long Standing Problem" made the front cover of Macromolecular Rapid Communications!

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Publication

[Apr 16, 2015]

Moritz's article titled "Solvent Selection Causes Remarkable Shifts of the "Ouzo Region" for Poly(Lactide-co-Glycolide) Nanoparticles Prepared by Nanoprecipitation" is accepted in Nanoscale. Congratulations!

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Publication

[Mar 23, 2015]

Moritz's Review article titled "Design Attributes of Long-Circulating Polymeric Drug Delivery Vehicles" is accepted in European Journal of Pharmaceutics and Biopharmaceutics. Congratulations!

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Publication

[Mar 19, 2015]

Vianney's article titled "One-Step Synthesis of Azlactone-Functionalized SG1-Based Alkoxyamine for Nitroxide-Mediated Polymerization and Bioconjugation" is accepted in Macromolecules. Congratulations!

This article is open access

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Publication

[Mar 19, 2015]

Elise's article titled "On the Structure-Control Relationship of Amide-Functionalized SG1-Based Alkoxyamines for Nitroxide-Mediated Polymerization and Conjugation" is accepted in Polymer Chemistry. Congratulations!

This article is open access

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Publication

[Fev 20, 2015]

Elise's Review article titled "Nitroxide-Mediated Polymerization of Methacrylic Esters: Insights and Solutions to a Long Standing Problem" is accepted in Macromolecular Rapid Communications. Well-done!

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Seminar

[Feb 3, 2015]

Julien presented a seminar titled "Design of Polymer Nanoparticles Against Cancer and the Alzheimer's Disease" at the Institut Charles Sadron (ICS) in Strasbourg, France.

Publication

[Jan 28, 2015]

We have published two book chapters titled "The Drug-Initiated Method: A Convenient Approach for the Synthesis of Efficient Polymer Prodrug Nanoparticles" and "Kinetic Studies of Elementary Reactions in SET-LRP / SARA ATRP" are published in Controlled Radical Polymerization; Matyjaszewski, K.; Sumerlin, B.; Tsarevski, N.; Chiefari, J. Eds.; ACS Symposium Series.

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