Home

  • Degradable and functional polyestersAngew. Chem., Int. Ed. 2017, in press
  • Fluorescent polymer prodrug nanoparticlesChem. Commun. 2017, 53, 4489
  • Degradable vinyl polymers for biomedical applicationsNature Chem. 2015, 7, 771
  • Anticancer polyterpene prodrug nanoparticlesAngew. Chem., Int. Ed. 2013, 52, 6
  • Anticancer multifunctional polyester nanoparticlesChem. Mater. 2014, 26, 1834
  • Lipid-containing polymer prodrug nanoparticlesChem. Mater. 2014, 26, 3606
  • Multifunctional squalene-based nanoparticlesChem. Commun 2014, 50, 5336
  • Nanoparticles for brain endothelial cell imagingChem. Commun. 2010, 46, 2602
  • Amyloid-beta peptide-binding nanoparticlesACS Nano 2012, 6, 5897
  • Nanoparticles against cancer and AlzheimerACS Nano 2012, 6, 5866
  • QD-loaded poly(alkyl cyanoacrylate) nanoparticlesSoft Matter 2011, 7, 6187
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Welcome to my homepage

I'm currently CNRS Research Director in the group of Pr. Patrick Couvreur at Institut Galien Paris-Sud (UMR CNRS 8612), at the Faculty of Pharmacy of Châtenay-Malabry, University Paris-Sud, France.

The Institut Galien Paris-Sud aims to design, synthesize, characterize and evaluate new drug delivery systems for the controlled release and the targeting of drugs. Pr. Patrick Couvreur's research group is working on the use of nanomedicines for cancer therapy as well as neurodegenerative and infectious diseases.

My contributions in this multidisciplinary research group are based on advanced macromolecular synthesis, physico-chemistry of colloids and bioconjugation, in order to develop efficient and innovative polymer biomaterials and nanomedicines.

News


Presentation

[May 28, 2018]

Julien delivered an invited lecture titled "Synthesis of Degradable Vinyl Polymers for Biomedical Applications" at the Bordeaux Polymer Conference (BPC 2018), Bordeaux, France.

Presentation

[Apr 11, 2018]

Julien delivered an invited lecture titled "Vinyl Polymers for Biomedical Applications" at the 15th European Symposium on Controlled Drug Delivery (ESCDD 2018), Egmond aan Zee, The Netherlands.

Press

[Mar 7, 2018]

Interview (in French) about Nanomedicine during the Radio show "La Méthode Scientifique" broadcasted on France Culture.

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Cover

[Feb 15, 2018]

Julien's invited Research article entitled "Self-Stabilized, Hydrophobic or PEGylated Paclitaxel Polymer Prodrug Nanoparticles for Cancer Therapy" made the front cover of Polymer Chemistry!

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Publication

[Jan 22, 2018]

Elise's article titled "Tunable Degradation of Copolymers Prepared by Nitroxide-Mediated Radical Ring-Opening Polymerization and Point-by-Point Comparison with Traditional Polyesters" is accepted in Macromolecules. Bravo!

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Publication

[Dec 22, 2017]

Yinyin's article titled "Hydrophobic or PEGylated, Self-Stabilized Paclitaxel Polymer Prodrug Nanoparticles for Cancer Therapy" is accepted in Polym. Chem. Congrats!

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Publication

[Dec 11, 2017]

Our collaborative article titled "Antibody-Functionalized Polymer Nanoparticle Leading to Memory Recovery in Alzheimer’s Disease-like Transgenic Mouse Model" is accepted in Nanomedicine NBM. Congrats to all!

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Grant

[Dec 18, 2017]

Julien has been awarded by an European Research Council (ERC) Consolidator grant (2018-2023) for a research project titled THERMONANO. The idea is to develop a new strategy for the administration of anticancer drug that is simple, efficient, comfortable for the patient and significantly less costly than traditional chemotherapies.

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Presentation

[Dec 4, 2017]

Johanna delivered a lecture titled "Radical Copolymerization of Vinyl Ethers and Cyclic Ketene Acetals: a New Platform to Challenge Traditional Polyesters for Biomedical Applications" at the SFNano 2017 meeting, Bordeaux, France. Bravo !

Event

[Nov 28, 2017]

Congratulations to Elise who successfully defended her PhD, titled "Degradable Polymer Prodrugs Synthesized by Nitroxide-Mediated Radical Ring-Opening Polymerization" in front of the following committee: Sophie Guillaume, Sagrario Pascual, Sébastien Lecommandoux, Philippe Guégan, Yohann Guillaneuf, Elias Fattal, Patrick Couvreur and Julien Nicolas.

Publication

[Nov 28, 2017]

Our feature article titled "Telechelic Polymers from Reversible-Deactivation Radical Polymerization for Biomedical Applications" is accepted in Chem. Commun. Congrats to all!

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Press release

[Nov 28, 2017]

Press release by the CNRS concerning our collaborative article in Angewandte Chemie, International Edition, titled: "Radical Copolymerization of Vinyl Ethers and Cyclic Ketene Acetals as a Versatile Platform to Design Functional Polyesters"

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Presentation

[Nov 22, 2017]

Julien delivered a lecture titled "New Polymers and Strategies for Drug Delivery Applications" at the GFP 2017 meeting, Paris, France.

Publication

[Nov 6, 2017]

Our collaborative paper (with Didier Gigmes and Didier Letourneur's groups) titled "Radical Copolymerization of Vinyl Ethers and Cyclic Ketene Acetals as a Versatile Platform to Design Functional Polyesters" is accepted in Angew. Chem., Int. Ed. Congrats to all!

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Presentation

[Oct 17, 2017]

Elise delivered a lecture titled "Development of Degradable Polymer Prodrug Nanoparticles for Cancer Therapy" at the 34ème Club Emulsion, Lyon, France. Congrats!

Publication

[Oct 14, 2017]

Julien published a collaborative article in l'Actualité Chimique (in French) titled: "Polymères et Interactions avec les Milieux Biologiques" as part of a themed issue titled "Polymères de Demain, Boosters d'Innovations".

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Presentation

[Sep 19, 2017]

Julien delivered an invited lecture titled "Innovative Polymers for Drug Delivery Applications" at the Chemistry division of the French Academy of Sciences, Paris, France.

Publication

[Sep 14, 2017]

Megan's paper (collaboration with Brent Sumerlin's group) titled "Radical Ring-Opening Copolymerization of Cyclic Ketene Acetals and Maleimides Affords Homogeneous Incorporation of Degradable Units" is accepted in ACS Macro Letters. Congrats!

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Presentation

[Aug 21, 2017]

Julien delivered an invited lecture titled "Comb-like PEG-based Vinyl Copolymers for Biomedical Applications" at the 252nd American Chemical Society National Meeting & Exposition, Philadelphia, PA, USA.

Presentation & Award

[Jun 23, 2017]

Elise delivered a lecture and received the second best oral communication award during the 2017 Doctoral School meeting in Châtenay-Malabry, France. Bravo !!

Award

[May 23, 2017]

Julien received the 2017 Polymer Chemistry Lectureship award by Associate Editor Christopher Barner-Kowollik during the Advanced Polymers via Macromolecular Engineering (APME) 2017 congress in Ghent, Belgium.

Presentation

[May 23, 2017]

Julien delivered an invited lecture titled "New Polymers and Strategies for Drug Delivery Applications" at the Advanced Polymers via Macromolecular Engineering (APME) 2017 congress in Ghent, Belgium.

Publication

[Apr 19, 2017]

Yinyin's paper titled "Structure-Cytotoxicity Relationship of Drug-Initiated Polymer Prodrug Nanoparticles" is accepted in Polym. Chem. Congrats Yinyin!

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Publication

[Mar 29, 2017]

Yinyin's paper titled "Fluorescent Polymer Prodrug Nanoparticles with Aggregation-Induced Emission (AIE) Properties from Nitroxide-Mediated Polymerization" is accepted in Chem. Commun. Congrats Yinyin!

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Publication

[Mar 29, 2017]

Our collaborative article titled "A Comprehensive Kinetic Study of the Conventional Free-Radical Polymerization of Seven-Membered Cyclic Ketene Acetals" is accepted in Polym. Chem. Congratulations to all!

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Seminar

[Mar 17, 2017]

Julien presented a seminar titled "Drug-Initiated Synthesis of Polymer Prodrug Nanoparticles" during the minisymposium "Polymers for Medicine" at the Institute of Materials, EPFL

Publication

[Jan 20, 2017]

Our Perspective article titled "Polymer Nanoparticles for the Delivery of Anticancer Drugs" is accepted in Med./Sci.

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Award

[Nov 17, 2016]

Julien received the French Polymer Society (GFP) / French Chemical Society (SCF) award during the 45th GFP meeting in Marseille, France.

Presentation

[Nov 17, 2016]

Julien delivered an invited lecture titled "Drug-Initiated Synthesis of Polymer Prodrug Nanoparticles" at the 45th GFP meeting in Marseille, France.

Publication

[Nov 11, 2016]

Our collaborative review article titled "Pulmonary Surfactant Protein A: A Mediated Enrichment of Surface-Decorated Polymeric Nanoparticles in Alveolar Macrophages" is accepted in Mol. Pharm. Congratulations to all!

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Publication

[Oct 7, 2016]

Our collaborative review article titled "Radical Ring-Opening Polymerization: Scope, Limitations and Application to (Bio)Degradable Materials" is accepted in Chem. Rev. Congratulations to all!

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Appointment

[Oct 5, 2016]

Julien has joined the editorial team of Chemistry of Materials (ACS) as Associate Editor.

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Presentation

[Sep 26, 2016]

Elise delivered a lecture titled "The Drug-Initiated Strategy: A Convenient Way to Design Polymer Nanoparticles for Anticancer Therapy" at the 4th Congress on Innovation in Drug Delivery: Site-Specific Drug Delivery, Antibes-Juan-les-Pins, France. Congratulations!

Presentation

[Aug 25, 2016]

Julien delivered an invited lecture titled "New Polymers and Strategies for Drug Delivery Applications" at the at the 254th American Chemical Society National Meeting & Exposition, Washington, DC, USA.

Publication

[Aug 15, 2016]

Yinyin's article titled "Simple Synthesis of Cladribine-Based Anticancer Polymer Prodrug Nanoparticles with Tuneable Drug Delivery Properties" is accepted in Chem. Mater. Congratulations!

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Presentation

[Jul 12, 2016]

Julien delivered an invited lecture titled "Vinyl Polymers for Biomedical Applications" at the Warwick Polymer Conference 2016, University of Warwick, Coventry, UK.

Presentation

[Jul 8, 2016]

Julien delivered an invited lecture titled "Polymer Nanoparticles for Biomedical Applications" at the 7ème journée GFP-IdF, ICPME, Université Paris-Est, Thiais.

Publication

[Jun 3, 2016]

Johanna's article titled "Efficient Synthesis of 2-Methylene-4-Phenyl-1,3-Dioxolane, a Cyclic Ketene Acetal for Controlling the NMP of Methyl Methacrylate and Conferring Tunable Degradability" is accepted in Polym. Chem. Bravo!

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Presentation

[May 24, 2016]

Julien delivered an invited lecture titled "Degradable PEG-Based Materials by Nitroxide-Mediated Radical Ring-Opening Copolymerization" at the Belgian Polymer Group annual meeting 2016, Hasselt, Belgium.

Presentation

[Apr 7, 2016]

Julien delivered an invited lecture titled "Drug-Initiated Synthesis of Polymer Prodrug Nanoparticles" at the 10th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical (PBP) Technology, Glasgow, UK.

Cover

[Mar 22, 2016]

Julien's invited Perspective article entitled "Drug-Initiated Synthesis of Polymer Prodrugs: Combining Simplicity and Efficacy in Drug Delivery" made the front cover of Chemistry of Materials!

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Presentation

[Mar 14, 2016]

Yinyin delivered a lecture titled "Efficient Anticancer Polymer Prodrug Nanoparticles from Drug-Initiated Controlled/Living Radical Polymerization" at the 251st American Chemical Society National Meeting & Exposition, San Diego, USA. Congratulations!

Presentation

[Mar 7, 2016]

Julien delivered an invited lecture titled "Drug-Initiated Synthesis of Polymer Prodrug Nanoparticles" at the 11th International Conference and Workshop on Biological Barriers, Saarbrücken, Germany.

Publication

[Jan 29, 2016]

Julien's invited Perspective article titled "Drug-Initiated Synthesis of Polymer Prodrugs: Combining Simplicity and Efficacy in Drug Delivery" is accepted in Chem. Mater.

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Seminar

[Jan 27, 2015]

Julien presented two seminars titled "Advanced polymer nanoparticles against cancer and the Alzheimer's disease" and "Vinyl polymers for biomedical applications" at the Institute of Toxicology and Genetics (ITG) and at the Macromolecular Architectures (MacroArc) Research Team at the Karlsruhe Institute of Technology (KIT), respectively.

Publication

[Jan 10, 2016]

Our collaborative paper titled "Nitroxide-Mediated Polymerization of Vinyl Chloride at Low Temperature: Kinetic and Computational Studies" is accepted in Macromolecules.

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Publication

[Dec 25, 2015]

Our collaborative paper titled "Cyclopentyl Methyl Ether as a Green Solvent for Reversible-Addition Fragmentation Chain Transfer and Nitroxide-Mediated Polymerizations" is accepted in RSC Advances.

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Presentation

[Dec 20, 2015]

Julien delivered three lectures (incl. one as invited speaker) titled "Nitroxide-Mediated Radical Ring-Opening Copolymerization: A Single Cyclic Ketene Acetal Comonomer to Control the Polymerization of Methacrylates and to Confer Degradability", "Conjugation and Bioconjugation from α-Functional Polymers Obtained by Nitroxide-Mediated Polymerization (NMP) Initiated by N-Hydroxysuccinimidyl- or Azlactone-Functionalized Alkoxyamines" and "The Drug-Initiated Method: a Convenient Approach for the Synthesis of Efficient Polymer Prodrug Nanoparticles" at the International Chemical Congress of the Pacific Basin Societies (Pacifichem 2015), Honoluu, Hawai, USA.

Member

[Dec 03, 2015]

Welcome to Alexandre Bordat, the newest member of the group, who joined us as PhD.

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Presentation

[Nov 05, 2015]

Julien delivered an invited plenary lecture titled "Advanced Polymer Nanoparticles For Efficient Drug Delivery" at the Applied Nanotechnology and Nanoscience International Conference (ANNIC 2015), Paris, France.

Member

[Nov 03, 2015]

Welcome to Johanna Tran, the newest member of the group, who joined us as PhD.

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Press

[Oct 9, 2015]

Following his review article in Nature Chemistry, Julien was interviewed by the CNRS Institute of Chemistry on potential biomedical applications from degradable vinyl polymers.

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Cover

[Oct 1, 2015]

Vianney's Review article entitled "Degradable Vinyl Polymers for Biomedical Applications" made the front cover of Nature Chemistry!

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Member

[Oct 01, 2015]

Welcome to Daniele Vinciguerra, the newest member of the group, who joined us as PhD.

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Publication

[Sep 22, 2015]

Vianney's Review article titled "Degradable Vinyl Polymers for Biomedical Applications" is accepted in Nature Chemistry. Congratulations!

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Vacancies

There are currently no vacancies but you can still join us with your own funding or by applying for national, european or international research grants

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